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. 2022 Feb 25;16:822891. doi: 10.3389/fnins.2022.822891

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Copyright © 2022 Ma, Wu, Xing, Huo, Gao, Ma, Li, Zheng, Hua and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolic connectivity of brain regions related to visceral sensation in the colorectal cancer group and healthy controls. (A,B) The r-value maps for the colorectal cancer group and healthy controls, respectively. (C) To find statistically significant differences in metabolic connectivity between models and controls, we calculated p-values for connections using a permutation test (p < 0.05). Significant differences in metabolic connectivity after false discovery rate (FDR) correction are represented by the upper triangular matrix, and those without FDR correction are represented by the lower triangular matrix. (D) The anatomical distribution of significantly different links between patients with colorectal cancer and healthy controls. r: correlation coefficient.