Table 2.
Demographics and general cognitive characteristics for each PPA subtype and healthy controls
| lvPPA | nfvPPA | svPPA | Controls | |
|---|---|---|---|---|
| No. of participants | 21 | 17 | 16 | 30 |
| Age, mean (SD) | 73 (67–79) | 71 (66–73) | 65 (63–70) | 68 (65–70) |
| Sex, male:female | 15:6 | 6:11 | 8:8 | 18:12 |
| Handedness, right:left | 19:1 | 15:2 | 17:0 | 27:3 |
| Education (years), mean (SD) | 19 (3) | 17 (2) | 19 (2) | 21 (3) |
| Time since diagnosis (years), mean (SD) | 1.2 (1) | 2 (1.7) | 2.4 (2) | — |
| Language symptom onset (years), mean (SD) | 2.4 (2) | 3.1 (2) | 5.8 (4) | — |
| BDAE sub-scores, mean (SD) | ||||
| Repetition of single words (/5) | 4 (0.6) | 4 (1) | 4 (0.8) | 5 (0) |
| Auditory comprehension (/16) | 15 (2) | 14 (4) | 11 (3) | 16 (0.2) |
| Picture–word matching (/4) | 3 (1) | 3 (1) | 2 (1) | 4 (0.3) |
| Repetition of sentences (/2) | 1 (0.6) | 1 (0.7) | 2 (0.6) | 2 (0) |
| Boston naming test (/15) | 8 (4) | 9 (5) | 3 (3) | 14 (0.4) |
| Oral reading (/15) | 14 (2) | 12 (5) | 13 (3) | 15 (0) |
| ACE-III/R sub-scores mean (SD) | ||||
| Attention (/18) | 12 (3) | 13 (5) | 15 (2) | 18 (0.6) |
| Memory (/26) | 9 (7) | 14 (8) | 9 (5) | 25 (0.7) |
| Fluency (/14) | 4 (3) | 3 (3) | 4 (2) | 13 (0.3) |
| Language (/26) | 18 (5) | 18 (6) | 11 (3) | 26 (0.4) |
| Visuospatial (/16) | 12 (2) | 12 (5) | 15 (1) | 16 (0) |
lvPPA, logopenic variant PPA; nfvPPA, non-fluent variant PPA; svPPA, semantic variant PPA; BDAE, Boston diagnostic aphasia examination; ACE, Addenbrooke’s cognitive examination; SD, standard deviation.