Figure 2.

Individual brain regions explaining unfavourable functional outcomes. Characteristic constellations of cortical (A) and subcortical brain regions, as well as white matter tracts (B) emerged that explained unfavourable outcomes ∼3 months after stroke in 500 male and 322 female stroke patients. Lesions in the left hemisphere were more strongly associated with unfavourable long-term outcomes than lesions in the right hemisphere for both men and women. Particularly relevant regions comprised left pre- and post-central, insular and opercular cortex, superior and middle temporal gyri, supramarginal and angular gyrus and lateral occipital cortex.