Fig. 1.

Screening of CYP2B6 inhibition by endo- and xenobiotics. Percent of control activity from chemically-exposed CYP2B6-transfected baculosomes. All exposures were performed at 10 µM with the exception of TCPOBOP, which was exposed at 1 µM. (A) Fatty acids and other endobiotics, (B) industrial chemicals and pharmaceuticals, and (C) pesticides. Statistical differences in absorbance were determined by ANOVA followed by fisher's LSD as the post-hoc test. (n = 2–14) *indicates p-value < 0.05; **indicates p-value < 0.01; ***indicates p-value < 0.001; ****indicates p-value  < 0.0001.