Fig. 2.

Concentration-dependent inhibition of CYP2B6 and CYP3A4. CYP2B6 or CYP3A4 containing baculosomes were exposed to fatty acids, bile acids, steroids, pesticides, industrial chemicals or pharmaceuticals at increasing concentrations. IC50’s and Hillslopes were determined as described in the materials and methods using GraphPad Prism 7.0 (n = 3–12).