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. 2022 Mar 4;41:108013. doi: 10.1016/j.dib.2022.108013
Subject Endocrinology and Metabolism
Specific subject area Inhibition of CYP2B6 and CYP3A4 by endobiotics and xenobiotics
Type of data Table
Graph
How data were acquired Gen5 fluorescent microplate reader (Synergy H1 Hybrid Reader, BioTek, Winooski, Vermont, USA). Data was stored in Excel and analyzed in GraphPad Prism 7.0 (San Diego, CA USA)
Data format Raw
Analyzed
Parameters for data collection CYP2B6 and CYP3A4 transfected baculosomes in Vivid® CYP450 Blue and Red screening kits from Life Technologies (Carlsbad, CA) were exposed to chemical inhibitors.
Description of data collection Fluorescent data was collected from a Gen5 microplate reader in kinetic mode during the performance of CYP2B6 and CYP3A4 Vivid P450 assays in the absence and presence of a number of potential CYP2B6 and CYP3A4 inhibitors. Collected data was analyzed on GraphPad Prism 7.0 to determine IC50s and Hillslopes.
Data source location Biological Sciences, Clemson University, Clemson, SC 29,634
Data accessibility Public repository
Repository name: Mendeley Data
Data identification number: doi: 10.17632/pfgg68yd2y.5
Direct URL to data:
https://data.mendeley.com/datasets/pfgg68yd2y/5
Related research article None; not at this time.