Subject | Endocrinology and Metabolism |
Specific subject area | Inhibition of CYP2B6 and CYP3A4 by endobiotics and xenobiotics |
Type of data | Table Graph |
How data were acquired | Gen5 fluorescent microplate reader (Synergy H1 Hybrid Reader, BioTek, Winooski, Vermont, USA). Data was stored in Excel and analyzed in GraphPad Prism 7.0 (San Diego, CA USA) |
Data format | Raw Analyzed |
Parameters for data collection | CYP2B6 and CYP3A4 transfected baculosomes in Vivid® CYP450 Blue and Red screening kits from Life Technologies (Carlsbad, CA) were exposed to chemical inhibitors. |
Description of data collection | Fluorescent data was collected from a Gen5 microplate reader in kinetic mode during the performance of CYP2B6 and CYP3A4 Vivid P450 assays in the absence and presence of a number of potential CYP2B6 and CYP3A4 inhibitors. Collected data was analyzed on GraphPad Prism 7.0 to determine IC50s and Hillslopes. |
Data source location | Biological Sciences, Clemson University, Clemson, SC 29,634 |
Data accessibility | Public repository Repository name: Mendeley Data Data identification number: doi: 10.17632/pfgg68yd2y.5 Direct URL to data: https://data.mendeley.com/datasets/pfgg68yd2y/5 |
Related research article | None; not at this time. |