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In vitro antifungal activities of NS-718, D-AmB, and L-AmB against 18 clinical isolates of A. fumigatus
| Drug | MIC (μg/ml)a
|
||
|---|---|---|---|
| Range | 50% | 90% | |
| NS-718 | 0.0313–0.25 | 0.125 | 0.25 |
| D-AmB | 0.0625–0.50 | 0.25 | 0.25 |
| L-AmB | 0.0625–1.0 | 0.25 | 1.0 |
The MICs were determined by the microdilution method modified from the macrodilution method of the National Committee for Clinical Laboratory Standards. The MICs were measured three times.
