Table 3. Univariate and multivariate logistic regression analysis of factors influencing the presence of mucus plugging.

Variables	Univariate models			Multivariate model
	OR*	95% CI	P value	OR*	95% CI	P value
Age (yr)	1.37	0.96, 1.96	0.084
Sex, male	1.01	0.71, 1.43	0.953
Body mass index (kg/m2)	0.83	0.58, 1.18	0.305
Pack-years	1.04	0.73, 1.48	0.830
%FEV1	0.40	0.26, 0.62	< 0.001
%FVC	0.38	0.24, 0.60	< 0.001	0.53	0.32, 0.91	0.020
FEV1/FVC	0.63	0.44, 0.92	0.016
%FEF 25–75	0.57	0.38, 0.86	0.007
R5 (cmH2O/L/s)	2.03	1.36, 3.04	0.001
R20 (cmH2O/L/s)	1.73	1.18, 2.53	0.005
R5–R20 (cmH2O/L/s)	2.17	1.42, 3.29	< 0.001
X5 (cmH2O/L/s)	0.43	0.26, 0.72	0.001
Fres (Hz)	2.62	1.65, 4.16	< 0.001	1.80	1.05, 3.11	0.034
ALX (cmH2O/L)	2.23	1.32, 3.76	0.003
Blood eosinophil count	2.17	0.99, 4.74	0.052
Total IgE	1.61	0.88, 2.95	0.119
FeNO	1.61	0.95, 2.72	0.077

OR, odds ratio; CI, confidence interval; ALX, low-frequency reactance area; FeNO, fractional exhaled nitric oxide; FEF 25–75, forced expiratory flow at 25%–75% of forced vital capacity; FEV1, forced expiratory volume in 1 second; Fres, resonant frequency; FVC, forced vital capacity; R5 and R20, respiratory resistance at 5 and 20 Hz; R5–R20, the difference between R5 and R20; X5, respiratory reactance at 5 Hz.

^*Per 1 standard deviation increase.