Figure 1. Nonconfocal Split Detection Adaptive Optics Scanning Laser Ophthalmoscopy Montage of the Photoreceptor Inner Segment Mosaic at Baseline and 1 Month Postinjection in the Injected Eye of Patient 06.

The same retinal features are observed longitudinally in both montages and the photoreceptor mosaic remains intact following the subretinal injection of adeno-associated virus-mediated hCHM. Asterisks denote the foveal location in the mosaic. Arrowheads highlight example features of the cone mosaic that are observed at both time points. Yellow boxes show an enlarged region of the cone mosaic within the montage; this location was one of the regions of interest used for cone density measurement. Blue and magenta boxes denote the locations of the regions of interest used for cone density measurements shown in Figure 2.