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. 2022 Feb 25;12:862076. doi: 10.3389/fonc.2022.862076

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Copyright © 2022 Jiang, Yuan, Tang, Wang, Zhang, Cho and Duan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miRNA-30a-5p was down-regulated in LUAD. (A) MiRNA-30a-5p was down-regulated in lung cancer based on TCGA-LAUD dataset. (B–G) Correlation between miRNA-30a-5p and clinicpathologic features, including the pathology stage, TNM stage, smoker, and therapy outcome in LUAD. (H) ROC curve analysis of miRNA-30a-5p showed an AUC value of 0.902 in LUAD. (I) miRNA-30a-5p was down-regulated in peripheral blood serum of LUAD analysed using qRT-PCR assay. *P < 0.05, ***P < 0.001. CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease. NS: p >0.05.