Cross-dataset analysis on the full retinal tissue segmentation results, presenting the mean (standard deviation) mean signed and absolute boundary errors (in pixels) results. Three different training/testing combinations were included for each model, including: (i) Using only the original dataset (O.D./O.D.), (ii) training adding the AMD dataset images (O.D. + AMD), and testing only on O.D. and (iii) training adding the AMD dataset images (O.D. + AMD), and testing only on AMD. The O.D. dataset denotes original healthy dataset imaged with the Spectralis device and the AMD dataset denotes the pathology dataset imaged with the Bioptigen device.