Fig. (4).

Photomicrographs of H&E stained stomach sections of rats: (a) Normal control showing the normal histological architecture of gastric layers. (b& c) treated with Lawsonia inermis L. Leaves and nano Lawsonia inermis L. Leaves respectively showing no histopathological alterations. (d) Ulcer group (positive control), showing necrosis of gastric mucosa, ulceration (red arrow), submucosal edema (blue arrow), inflammatory cells infiltration (yellow arrow) and congested blood vessel (black arrow). (e) Ulcer treated with Lawsonia inermis L. Leaves, showing slight submucosal edema (blue arrow). (f) Ulcer + nano Lawsonia inermis L. Leaves showing normal gastric layers (scale bar, 100 µm).