Table 2.

Results for PCL-5 (PTSD checklist for DSM-5) change from multivariable generalised estimating equation modelling

Variable	Mean difference (95% CI)	P value
ITT (best-case/worst-case)
iCBT (ref.: no)	−0.96 (−5.88 to 3.97)	0.703
Baseline value (t0)	0.09 (−0.05 to 0.23)	0.225
ITT (MICE)
iCBT(ref.: no)	4.01 (−1.89 to 9.91)	0.181
Baseline value (t0)	0.16 (−0.02 to 0.33)	0.078
PP
iCBT(ref.: no)	2.40 (−2.29 to 7.08)	0.316
Baseline value (t0)	0.10 (−0.03 to 0.23)	0.123

Model coefficients (mean difference) together with 95% CIs and p values are provided. Positive values indicate effects in favour of iCBT. Results from both ITT approaches (best-case/worst-case as main analysis, MICE as sensitivity analysis) and the PP analysis (sensitivity analysis) are provided. For binary variables, the reference category (ref.) is provided. Note that there were five participants in the iCBT group and none in the waitlist control group with missing information (missing PCL-5 change: 5, missing baseline value: 1; Supplemental Digital Content 1, online supplemental figures A3, A4).

iCBT, internet-based cognitive-behavioural writing therapy; ITT, intention-to-treat; MICE, multiple imputation by chained equations; PP, per-protocol; PTSD, post-traumatic stress disorder.