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. 2022 Mar 11;2022(3):CD013130. doi: 10.1002/14651858.CD013130.pub2

Kakourou 1997.

Study characteristics
Methods Study Design: prospective comparative study
Study Duration: not reported
Number of Participants: 16
Study Dates: 1989 to 1994
Participants Setting: inpatient paediatric unit in Athens, Greece 
Inclusion Criteria: children admitted to the department within 3 days from onset of rash who had a diagnosis of EMM based on the following criteria: 
  • an erythematous papulovesicular or bullous skin eruption with at least 1 target lesion;

  • ulcerative lesions involving at least 2 mucosal surfaces.


Exclusion Criteria: not reported
Baseline Data:
Disease classification, number of participants with SJS: SJS‐TEN overlap: TEN
  • All classified as EMM


Intervention:
  • Mean age, years (range): 6 (+/− 4) 

  • Sex distribution, Males: Females, 7:3


Comparator: 
  • Mean age, years (range): 6.6 (+/− 5.2)

  • Sex distribution, Males: Females, 3:3


Data not reported:
  • SCORTEN

  • BSA at baseline

  • Disease duration prior to treatment

  • Baseline comorbidities

Interventions Intervention: 
Corticosteroids (bolus infusion of methylprednisolone (4 mg/kg/day) for 2 more days after the fever had subsided and no new lesions had developed) (n = 10)
Comparator: 
Supportive care only (n = 6)
Outcomes Mortality
Funding source None reported.
Declarations of interest None declared.
Notes