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. 2022 Feb 28;19(2):101–114. doi: 10.11909/j.issn.1671-5411.2022.02.009

Table 4. Univariate and multivariate Cox regression of the association between Lactobacillus and major adverse cardiovascular event.

Lactobacillus level Events Univariate analysis Multivariate analysis
HR (95% CI) P-value HR (95% CI) P-value
Multivariate Cox proportional hazard model adjusted for age, left ventricular ejection fraction, high-sensitivity C-reactive protein, TroponinT, low-density lipoprotein, and brain natriuretic peptide. HR: hazard ratio.
Total
 Low 17 (30.91%) Reference Reference
 Medium 18 (26.09%) 0.729 (0.375−1.419) 0.353 0.675 (0.331−1.377) 0.280
 High 10 (7.69%) 0.202 (0.092−0.441) < 0.001 0.216 (0.094−0.493) < 0.001
ST-segment elevation myocardial infarction
 Low 15 (30.61%) Reference Reference
 Medium 12 (21.43%) 0.583 (0.272−1.252) 0.166 0.536 (0.237−1.214) 0.135
 High 7 (8.05%) 0.210 (0.085−0.515) 0.001 0.217 (0.085−0.551) 0.001
Non-ST-segment elevation myocardial infarction
 Low 2 (33.33%) Reference Reference
 Medium 6 (46.15%) 1.467 (0.296−7.279) 0.639 2.180 (0.212−22.371) 0.512
 High 3 (6.98%) 0.183 (0.030−1.100) 0.063 0.222 (0.020−2.443) 0.219