Table 2.
List of toxins that modulate Nav1.7 channel activity.
| Toxin name | Abbreviation(s) | Biological source |
|---|---|---|
| Inhibitors of channel function | ||
| μ-theraphotoxin-Pn3a | Pn3a | Tarantula Pamphobeteus nigricolor |
| Phoneutria nigriventer toxin 1 | PnTx1 | Brazilian spider Phoneutria nigriventer |
| Grammostola porter Toxin 1 | GpTx-1 | Rose hair or Chilean tarantula Grammostola porteri |
| Jingzhaotoxin-V | JzTx-V | Chinese tarantula Chilobrachys jingzhao |
| μ-theraphotoxin-Tp1a | μ -TRTX-Tp1a (also known as Tp1a or ProTX-III) | Peruvian green velvet Thrixopelma pruriens |
| Theraphosa apophysis Toxin 1a | Tap1a | Venezuelan tarantula Theraphosa apophysis |
| Davus fasciatus Toxin 1a | μ-TRTX-Df1a (also known as Df1a) | Costa Rican tiger rump tarantula Davus fasciatus |
| Huwentoxin-IV | HWTX-IV | Chinese bird spider Haplopelma schmidti |
| Hainantoxins | HNTX I and III | Chinese bird spider Ornithoctonus hainana |
| Activator of channel function | ||
| α-scorpion toxin OD1 | OD1 | Scorpion Odonthobuthus doriae |