TABLE 3.
Allele and genotype distribution frequencies of SNPs in women with mild and severe endometriosis.
| SNP | Model | Mild EN | Severe EN | X 2 | OR (95%CI) | p-value |
|---|---|---|---|---|---|---|
| N = 112 | N = 108 | |||||
| rs895819 | Allele A | 139 (62) | 181 (83.7) | 26.2 | 0.31 (0.20–0.49) | p < 0.001 |
| Allele G | 85 (38) | 35 (16.3) | ||||
| Co-dominant (AG v AA+GG) | 73 (65.1) | 23 (21.2) | 44.8 | 0.14 (0.07–0.26) | p < 0.001 | |
| Dominant (AA v AG+GG) | 33 (29.5) | 79 (73.1) | 41.9 | 0.15 (0.08–0.27) | p < 0.001 | |
| Recessive (GG v AA+AG) | 6 (4.4) | 6 (5.5) | 0.04 | 1.03 (0.32–3.32) | 0.94 | |
| rs6505162 | Allele A | 120 (53.5) | 155 (71.7) | 15.52 | 0.45 (0.30–0.67) | p < 0.001 |
| Allele C | 104 (46.5) | 61 (28.3) | ||||
| Co-dominant (AC v AA+CC) | 72 (64.2) | 43 (39.8) | 22.0 | 0.36 (0.21–0.63) | p < 0.001 | |
| Dominant (AA v AC+CC) | 24 (21.5) | 56 (51.8) | 21.99 | 0.25 (0.14–0.45) | p < 0.001 | |
| Recessive (CC v AA+AC) | 16 (14.2) | 9 (8.3) | 1.93 | 0.54 (0.23–1.29) | 0.16 |
EN, endometriosis.