TABLE 4.

Distribution of ACE2 and TMPRSS2 SNPs in different genetic models.

	OR (95% CI)	p value
ACE2 (rs2285666)
CC vs. TT (Recessive-1)	10.83 (5.36–20.71)	<0.001
CC + CT vs. TT (Recessive-2)	10.15 (5.34–19.30)	<0.001
CC vs. CT + TT (Dominant)	5.01 (3.18–7.89)	<0.001
CC vs CT (Co–dominant)	1.68 (0.89–3.19)	0.108
CT vs. CC + TT (over dominant)	0.94 (0.50–1.76)	0.848
TMPRSS2 (rs12329760)
CC vs. TT (Recessive-1)	5.03 (1.40–18.14)	0.007
CC + CT vs. TT (Recessive-2)	4.21 (1.17–15.13)	0.017
CC vs. CT + TT (Dominant)	3.30 (1.97–5.52)	<0.001
CC vs CT (Co–dominant)	3.05 (1.76–5.29)	<0.001
CT vs. CC + TT (over dominant)	0.35 (0.20–0.60)	<0.001

Genotype on the left is the reference.

OR, Odds ratio; CI 95%, Confidence interval at 95%; ACE2, Angiotensin-converting enzyme 2; TMPRSS2, Transmembrane serine protease 2; C, cytosine; T, thymine.