TABLE 6.
Distribution of Laboratory data according to ACE2 and TMPRSS2 SNPs.
| ACE2 (rs2285666) | p Value | TMPRSS2 (rs12329760) | p Value | |||
|---|---|---|---|---|---|---|
| CC (no = 196) | CT + TT (n = 103) | CC (no = 236) | CT + TT (n = 63) | |||
| Hb (gm/dl) | 12.4 ± 1.8 | 12.7 ± 1.9 | 0.124 | 12.5 ± 1.8 | 12.8 ± 2.04 | 0.214 |
| RBCs*106 | 5.0 ± 1.8 | 5.1 ± 1.7 | 0.795 | 5.1 ± 1.8 | 4.9 ± 1.7 | 0.602 |
| HCT% | 37.9 ± 7.1 | 38.2 ± 8.1 | 0.771 | 37.9 ± 7.5 | 38.5 ± 7.1 | 0.531 |
| Platelets*103 | 209.5 (172.2–250) | 190 (161–250) | 0.034 | 214 (170–256.5) | 175 (153–230) | 0.001 |
| WBCs*103 | 5.6 (4.2–7.1) | 6.4 (4.7–8) | 0.020 | 5.9 (4.4–7.7) | 5.5 (3.8–7) | 0.149 |
| Lymphocytes | 1141.8 (708–1820) | 1137 (708.8–1137) | 0.877 | 1146.9 (716.4–1752) | 1083 (638.4–1700) | 0.165 |
| Neutrophils | 3053 (2178–4697) | 2897.5 (1953–1243.6) | 0.414 | 3019 (2061.5–4434.5) | 2808 (2025–4031) | 0.351 |
| CRP (mg/L) | 34.5 (12–96) | 66 (18–130) | 0.048 | 42.5 (12–95.8) | 73 (24–150) | 0.031 |
| Ferritin | 172 (100–310) | 555 (192–877) | <0.001 | 190 (103–414) | 645.5 (148–900) | <0.001 |
| LDH | 324 (250–381) | 460 (261–776) | <0.001 | 342 (250–430) | 381 (274–800) | 0.004 |
| D-Dimer | 200 (100–445) | 1100 (320–1450) | <0.001 | 250 (140–552.5) | 1190 (200–1750) | <0.001 |
Data are expressed as no, %, Mean ± SD or Median (Interquartile range).
ACE2, Angiotensin converting enzyme 2; TMPRSS2, Transmembrane serine protease 2; C, cytosine; T, thymine; Hb, Hemoglobin; RBCs, Red blood cells,; HCT, Hematocrit; WBCs, white blood cells, lymphocytes and neutrophils were presented in absolute figures; NLR, Neutrophil lymphocyte ratio; PLR, Platelets lymphocyte ratio; CRP, C- reactive protein; LDH, lactate dehydrogenase.
Unpaired t test was used for parametric data while Mann-Whitney was used for non-parametric data.