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. 2021 Mar 22;3:636976. doi: 10.3389/ftox.2021.636976

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Copyright © 2021 Dussert, Wegner, Moriscot, Gallet, Jouneau, Reiss and Carriere.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantum dot (QD) genotoxicity, assessed via the comet assay. DNA integrity was assessed via the alkaline (A,C) or the Fpg-modified comet assay (B,D). Cells were exposed for 24 h to 25 nM of pristine QDs and 3 nM of aged QDs. Methyl methanesulfonate (MMS, 100 μM) was used as positive control. Data are mean ± standard deviation of six independent experiments, performed on human primary keratinocytes from three different donors, with two technical replicates per experiment. Statistical significance: p < 0.05, *exposed vs. control.