FIGURE 1.

The OECD funded AOP-KB currently support the AOP-Wiki. The EPA AOP-DB, currently slated as a third-party tool for integration with the AOPKB 2.0, automatically and programmatically pulls AOP data from the AOP-KB XML, and extends AOP capabilities to users with semantic resources like WikiPathways and the OpenRiskNet e-infrastructure that incorporate the Research Description Framework (RDF). Integration of data across the AOP-KB (AOP-Wiki), AOP-DB, and expanding research frameworks through WikiPathways and the EU funded OpenRiskNet, creates additional ontological linkages and improves capabilities for computational analyses. These tools are useful to AOP users trying to retrieve information for AOP development, as well as those trying to understand and characterize existing AOPs.