Table 6.
Per-puff % reductions in WHO TobReg 9 constituents from ePen e-cigarettes relative to combustible cigarette emissions estimated by the mid-point estimation approach and two boundary conditions for unquantifiable and undetectable toxicants.
| % Reductions in comparison to 1R6F | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Toxicant | ePen2 BT 18 | ePen3 BT 18 | ePen3 MB 12 Low BA | ePen3 MB 18 Medium BA | ePen3 MB 30 High BA | ||||||||||
| Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper ‡ | |
| CO | >99.9 | 99.82 | 99.64 | >99.9 | 99.82 | 99.64 | >99.9 | 99.82 | 99.64 | >99.9 | 99.82 | 99.64 | >99.9 | 99.82 | 99.64 |
| Acetaldehyde | 99.86 | 99.86 | 99.86 | 99.99 | 99.99 | 99.98 | 99.94 | 99.94 | 99.94 | 99.99 | 99.99 | 99.98 | 99.98 | 99.98 | 99.98 |
| Acrolein | 97.61 | 97.61 | 97.61 | 100 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | 99.94 | 99.86 | 99.79 | 99.94 | 99.86 | 99.79 |
| Formaldehyde | 94.51 | 94.51 | 94.51 | 98.92 | 98.92 | 98.92 | 96.33 | 96.33 | 96.33 | 97.76 | 97.76 | 97.76 | 97.47 | 97.47 | 97.47 |
| Benzo[a]pyrene | >99.9 | 99.69 | 99.38 | >99.9 | 99.69 | 99.38 | >99.9 | 99.69 | 99.38 | >99.9 | 99.69 | 99.38 | >99.9 | 99.69 | 99.38 |
| NNK | >99.9 | 99.96 | 99.93 | >99.9 | 99.96 | 99.93 | >99.9 | 99.96 | 99.93 | >99.9 | 99.96 | 99.93 | >99.9 | 99.96 | 99.93 |
| NNN | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 |
| Benzene | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 |
| 1,3-Butadiene | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 |
| Mean estimate | 99.11 | 99.04 | 98.98 | 99.88 | 99.81 | 99.74 | 99.59 | 99.52 | 99.45 | 99.74 | 99.67 | 99.59 | 99.71 | 99.64 | 99.56 |
| % Reductions in comparison to B&H Skyblue | |||||||||||||||
| Toxicant | ePen2 BT 18 | ePen3 BT 18 | ePen3 MB 12 Low BA | ePen3 MB 18 Medium BA | ePen3 MB 30 High BA | ||||||||||
| Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper | Lower* | Mid † | Upper ‡ | Lower* | Mid † | Upper ‡ | |
| CO | >99.9 | 99.81 | 99.62 | >99.9 | 99.81 | 99.62 | >99.9 | 99.81 | 99.62 | >99.9 | 99.81 | 99.62 | >99.9 | 99.81 | 99.62 |
| Acetaldehyde | 99.87 | 99.87 | 99.87 | 99.99 | 99.99 | 99.98 | 99.94 | 99.94 | 99.94 | 99.99 | 99.99 | 99.98 | 99.98 | 99.98 | 99.98 |
| Acrolein | 97.83 | 97.83 | 97.83 | 100 | 99.97 | 99.94 | 100 | 99.97 | 99.94 | 99.94 | 99.87 | 99.81 | 99.94 | 99.87 | 99.81 |
| Formaldehyde | 94.88 | 94.88 | 94.88 | 98.99 | 98.99 | 98.99 | 96.58 | 96.58 | 96.58 | 97.91 | 97.91 | 97.91 | 97.64 | 97.64 | 97.64 |
| Benzo[a]pyrene | >99.9 | 99.71 | 99.43 | >99.9 | 99.71 | 99.43 | >99.9 | 99.71 | 99.43 | >99.9 | 99.71 | 99.43 | >99.9 | 99.71 | 99.43 |
| NNK | >99.9 | 99.92 | 99.83 | >99.9 | 99.92 | 99.83 | >99.9 | 99.92 | 99.83 | >99.9 | 99.92 | 99.83 | >99.9 | 99.92 | 99.83 |
| NNN | >99.9 | 99.95 | 99.89 | >99.9 | 99.95 | 99.89 | >99.9 | 99.95 | 99.89 | >99.9 | 99.95 | 99.89 | >99.9 | 99.95 | 99.89 |
| Benzene | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 | >99.9 | 99.98 | 99.96 |
| 1,3-Butadiene | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 | >99.9 | 99.97 | 99.94 |
| Mean estimate | 99.18 | 99.1 | 99.03 | 99.89 | 99.81 | 99.73 | 99.61 | 99.54 | 99.46 | 99.76 | 99.68 | 99.6 | 99.73 | 99.65 | 99.57 |
BT, Blended Tobacco; MB, MasterBlend, BA, benzoic acid.
*
Lower boundary estimate approach, where results <LOD are taken as 0 and <LOQ values are taken as LOD.
Mid-point estimate, where results <LOD are estimated as LOD/2, and results <LOQ are estimated as (LOD+LOQ)/2.
‡
Upper boundary estimate approach, where <LOD = LOD and <LOQ = LOQ.