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. 2022 Feb 25;9:851255. doi: 10.3389/fnut.2022.851255

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Copyright © 2022 Chen, Huang, Bian and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Berberine (BBR) alleviated the permeability and lung tissue injury in C57BL/6 mice with ALI. (A) The H&E staining and lung injury score in pulmonary section, n = 3, scale bar = 100 μm. (B) The ratio of wet lung to dry lung, n = 8. (C,D) The detection of total protein and cell counts in BALF, n = 8. (E) The concentration of Evans blue in lung tissue, n = 8. Data were expressed as mean ± SD. Statistical significance is indicated as *P < 0.05 vs. the sham + vehicle groups, ^#P < 0.05 vs. the lipopolysaccharide (LPS) + vehicle groups. ALI, acute injury lung; BALF, bronchoalveolar lavage fluid.