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SV recycling is nested in the endolysosomal system. SV recycling is a nested cycle within a larger cycle that encompasses membrane-bound organelles that reside in both, presynaptic sites (the Recycling and Resting pool) and neuronal cell bodies (the Golgi apparatus and degradative lysosomes). The Golgi apparatus performs protein surveillance and funnels cargos to pathways that either repair damage or degrade old and damaged proteins (the lysosome).
