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. Author manuscript; available in PMC: 2022 May 15.
Published in final edited form as: Mol Cell Endocrinol. 2021 Mar 4;528:111212. doi: 10.1016/j.mce.2021.111212

Figure 7. ERβ-regulated granulosa cell genes that are crucial for gonadotropin induced follicle maturation.

Figure 7.

Expression of FSH/FSHR-induced genes including Cyp11a1, Cyp19a1, Lhcgr, Gata4, Npr2, Jaml, Galnt6, Znf750, and Dusp9 as well as expression of LH/LHCGR-induced genes including Pgr, Runx2, Egfr, Kiss1, Ptgs2, Adamts1, Wnt16, and Mageb16 are dependent on ERβ-signaling. These genes play a crucial role in the preovulatory maturation of ovarian follicles.