Table 1.
Demographic and clinical data according to the type of treatment.
| IVT (n = 241) |
MT (n = 21) |
IVT + MT (n = 29) | P | |
|---|---|---|---|---|
| Age (years) | 68 ± 12.8 | 61 ± 15.4 | 65 ± 12.9 | 0.037 |
| Females (%) | 133 (55.0) | 10 (48.0) | 21 (72.0) | 0.171 |
| White (%) | 217 (90.0) | 15 (71.0) | 25 (86.0) | 0.031 |
| NIHSS at admission | 12.4 ± 6.8 | 13.5 ± 7.3 | 14.4 ± 6.8 | 0.32 |
| NIHSS after IVT | 8.8 ± 6.6 | - | 17.8 ± 6.2 | <0.001 |
| Diabetes mellitus (%) | 68 (28.0) | 8 (38.0) | 11 (38.0) | 0.436 |
| Hypertension (%) | 185 (77.0) | 15 (71.0) | 20 (69.0) | 0.616 |
| Non-smoker (%) | 123 (51.0) | 9 (43.0) | 17 (59.0) | 0.604 |
| SBP at admission (mm Hg) | 159 ± 29.6 | 146 ± 40.5 | 153 ± 29.1 | 0.098 |
| DBP at admission (mm Hg) | 90 ± 16.4 | 83 ± 18.1 | 86 ± 19.3 | 0.134 |
| Serum creatinine (mg/dl) | 1.1 ± 0.7 | 0.9 ± 0.3 | 1.0 ± 0.3 | 0.259 |
| ASPECTS | 8.8 ± 1.3 | 7.3 ± 1.5 | 8.0 ± 1.8 | <0.001 |
| Symptom-to-door time (min)† | 135 ± 90 | 218 ± 165 | 141 ± 105 | 0.001 |
| Door-to-treatment time (min)† | 61 ± 44 | 246 ± 171 | 222 ± 111 | <0.001 |
| ECASS (%) | ||||
| 0 | 185 (76.8) | 12 (57.1) | 18 (62.1) | 0.019 |
| 1 | 8 (3.32) | 1 (4.8) | 3 (10.3) | |
| 2 | 14 (5.81) | 3 (14.3) | 0 (0.0) | |
| 3 | 25 (10.4) | 5 (23.8) | 4 (13.8) | |
| 4 | 9 (3.67) | 0 (0.0) | 4 (13.8) | |
| Recanalization rate (%) | ||||
| TICI 0 | NA | 2 (9.5) | 2 (6.9) | |
| TICI 1 | NA | 2 (9.5) | 4 (13.8) | |
| TICI 2a | NA | 1 (4.8) | 2 (6.9) | 0.678 |
| TICI 2b | NA | 6 (28.6) | 5 (17.2) | |
| TICI 3 | NA | 10 (47.6) | 16 (55.2) | |
| Hemicraniectomy | 5 (2.1) | 3 (14.3) | 6 (20.7) | <0.001 |
| Death in hospitalization | 29 (12.0) | 2 (9.5) | 11 (37.9) | 0.001 |
| Death at 90 days | 36 (14.9) | 4 (19.0) | 14 (48.3) | <0.001 |
| mRS > 2 at 90 days‡ (%) | 35/203 (17) | 7/17 (41) | 6/15 (40) | 0.014 |
IVT, intravenous thrombolysis; MT, mechanical thrombectomy; NIHSS, National Institute of Health Stroke Scale; SBP, systolic blood pressure; DBP, diastolic blood pressure; ASPECTS, Alberta Stroke Program Early Computed Tomography Score; ECASS, European Cooperative Acute Stroke Study; TICI, Thrombolysis in Cerebral Infarction scale.
†
non-parametric test.
‡
only survivors.