Table 1.

Comparison of pro-calcitonin levels based on bacterial co-infections (Cohort 1)

	Absence/low-suspicion of bacterial co-infection	Proven bacterial co-infection	P value
Non-ICU, n (%)	892 (96.5)a	32 (3.5)
Median (IQR, Range)	0.16 (0.08–0.36, < 0.06–87.4)	0.64 (0.16–2.87, < 0.06–92.0)	0.014
< 0.25 µg/L, n (%)	576 (64.6)	10 (31.3)	< 0.001
≥ 0.25 µg/L, n (%)	316 (35.4)	22 (68.8)
ICU, n (%)	95 (92.2)b	8 (7.8)
Median (IQR, Range)	0.37 (0.17–1.04, < 0.06–242.4)	1.3 (0.19–19.5, 0.08–202.2	0.257
< 0.25 µg/L, n (%)	31 (32.6)	2 (25)	1.0
≥ 0.25 µg/L, n (%)	64 (67.4)	6 (75)

^a7.8% were classified as absence of co-infection and 88.7% as low-suspicion of co-infection

^b3.9% were classified as absence of co-infection and 88.3% were classified as low suspicion of co-infection