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. Author manuscript; available in PMC: 2022 Mar 11.
Published in final edited form as: Int J Cancer. 2021 Jun 10;149(6):1302–1312. doi: 10.1002/ijc.33702

Figure 3.

Figure 3.

The eQTL analysis for CHEK1 rs76744140 and CDK6 rs113181986 from the GTEx (V8) database and comparison of mRNA expression levels of CHEK1, PRIM2 and CDK6 between lung cancer tissue and adjacent normal lung tissues in the TCGA dataset. (A) The correlation of rs76744140 genotypes and CHEK1 mRNA expression in normal lung tissues; (B) The correlation of rs113181986 genotypes and CDK6 mRNA expression in whole blood tissues; (C) Higher expression of CHEK1 were found both in the LUAD and LUSC tumor tissues compared to the normal tissues; (D) Higher expression of PRIM2 were found both in the LUAD and LUSC tumor tissues compared to the normal tissues; (E) Higher expression of CDK6 were found in the LUSC tumor tissues compared to the normal tissues.