Figure 8.

Short-term (1-back) adaptation does not introduce spurious long-term adaptation effects for the particular stimulus sequences used in the experiments. A, B, We simulated responses of an artificial neuron to the particular stimulus sequences used in the drifting grating experiment (A) and static grating experiment (B). The artificial neuron responded equally to all stimulus orientations, but selectively reduced its responses to a successive repeated orientation to mimic orientation-specific 1-back adaptation. We chose the strength of this 1-back adaptation effect to match the empirically observed 1-back adaptation of V1. We subsequently analyzed the simulated responses with the same procedure used for the empirical data. The analysis of the simulated responses recovered the ground truth 1-back adaptation effect (black data points). There were no spurious adaptation effects for stimuli farther in the past, as indicated by the black data points being centered on an adaptation ratio of one, markedly different from the empirically observed long-term adaptation effects (red data points, adaptation in V1). Black error bars indicate 95% CIs of adaptation across the simulations of the 32 stimulus sequences. Red error bars indicate 95% CIs of empirical adaptation across neurons in V1.