Table I.
Baseline patient and biochemical characteristics of study patients
| Characteristic (N = 613) | |
|---|---|
| Age at diagnosis, mean (SD) | 64 (12.3) |
| Men, N (%) | 134 (21.9) |
| Symptomatic, N (%) | 587 (95.8) |
| Thiazide use, N (%) | 93 (15.2) |
| Serum Ca, median (IQR), mg/dL | 10.7 (10.4–11.1) |
| Serum Cr, median (IQR), mg/dL | 0.9 (0.7–1.0) |
| GFR, median (IQR), mL/min | 70.0 (60.0–89.0) |
| Vitamin D 25-OH, median (IQR), ng/mL | 36 (27.0–46.9) |
| Serum PTH, median (IQR), pg/mL | 108.6 (82.0–148.0) |
| 24-hour urine calcium, median (mg/24h) | 252.8 (162.0–379.9) |
| 24-hour urine creatinine, median (IQR), mg/24h | 1180.0 (936.0–1500.0) |
| 24-hour urine volume, median (IQR), L/24h | 1.9 (1.4–2.5) |
| CCCR, median (IQR) | 0.017 (0.012–0.023) |
| Repeat 24-hour urine obtained, N (%) | 25 (4.1) |
| Parathyroid exploration, N (%) | 553 (90.4) |
| Surgical failure, N (%) | 8 (1.8) |
IQR, interquartile range; Ca, calcium; Cr, creatinine; GFR, glomerular filtration rate; CCCR, calcium-to-creatinine ratio; PTH, parathyroid hormone; SD, standard deviation.