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. 2022 Mar 4;2022:3613319. doi: 10.1155/2022/3613319

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Copyright © 2022 Fan Yang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mitochondrial transfer improves mitochondrial dysfunction in NPCs. (a) Flow cytometric analysis of mitochondrial membrane potential in NPCs. (b) Histogram showing the mitochondrial membrane potential. Means ± SD, n = 4. (c) Flow cytometric analysis of ROS levels in NPCs. (d) Relative levels of intracellular ROS. Means ± SD, n = 4. (e–g) Histogram showing the ATP, ADP, and ADP/ATP levels in NPCs. (h–j) Histogram showing the levels of NAD+, NADH, and NADH/NAD+ in NPCs. Means ± SD, n = 6. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, and ^∗∗∗∗P < 0.0001. BMSCs: bone marrow mesenchymal stem cells; CB: cytochalasin B; NPCs: nucleus pulposus cells; rot: rotenone.