Table 2.
Mechanical property measurements for printed and biological mitral valve leaflet constructs.
| Material property | Shore hardness | Elastic modulus (MPa) | Maximum observed strain (%) |
Maximum observed force (N) | Maximum observed stress (MPa) | Failure achieved |
|---|---|---|---|---|---|---|
| Leaflets A | 27 | 0.51 ± 0.01 | 58 ± 3 | 1.38 ± 0.12 | 0.30 ± 0.01 | N |
| Leaflets B | 27/40 | 0.63 ± 0.01 | 64 ± 3 | 4.25 ± 0.41 | 0.41 ± 0.01 | N |
| Leaflets C | 27/70 | 0.51 ± 0.05 | 58 ± 1 | 3.11 ± 0.33 | 0.31 ± 0.04 | N |
| Leaflets D | 27/70 | 0.95 ± 0.02 | 60 ± 8 | 7.07 ± 1.30 | 0.54 ± 0.11 | Y |
| Mitral Anterior Leaflet | N/A | 2.20 ± 0.55 | 49 ± 4 | 5.90 ± 1.60 | 0.96 ± 0.12 | Y |
| Mitral Posterior Leaflet | N/A | 1.74 ± 0.48 | 56 ± 6 | 3.74 ± 1.34 | 0.61 ± 0.16 | Y |
All printed leaflets were fabricated using Agilus. Leaflets A were printed with a homogeneous shore 27 formulation, Leaflets B were printed as bilayer constructs of shore 27 and shore 50 hardness, Leaflets C were printed with a shore 27 inner core and shore 70 outer shell, and Leaflets D were printed to patient-specific geometries with a shore 27 inner core and shore 70 outer shell. Results are presented as mean ± SD. N = 3