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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Cancer. 2021 Dec 16;128(7):1532–1544. doi: 10.1002/cncr.34066

Table 4.

Estimates of fixed effects from linear mixed models examining treatment condition as a predictor of change in sleep outcomes over time.

Insomnia Severity Index (ISI)
Model 1 B SE df T p r p 2 Model 2 B SE df t p r p 2
Intercept 17.85 .97 72.91 18.38 <.001 .82 Intercept 13.05 1.01 78.28 12.93 <.001 .68
t0 – t1 −3.48 1.00 74.70 −3.48 .001 .14 t2 – t0 4.80 .98 74.19 4.89 <.001 .24
t0 – t2 −4.80 .98 74.19 −4.89 <.001 .24 t2 – t1 1.32 1.01 72.28 1.30 .20 .02
Condition (t0) .25 1.37 72.91 .18 .86 .0004 Condition (t2) −5.74 1.43 78.41 −4.03 <.001 .17
t0 – t1 * Condition −5.66 1.39 73.84 −4.08 <.001 .18 t2 – t0* Condition 5.99 1.39 73.81 4.32 <.001 .20
t0 – t2 * Condition −5.99 1.39 73.81 −4.32 <.001 .20 t2 – t1* Condition .33 1.41 72.27 .23 .82 .0007
Pittsburgh Sleep Quality Index (PSQI) Item 6 (Sleep Quality)
Model 1 B SE df T p r p 2 Model 2 B SE df t p r p 2
Intercept 1.95 .15 66.51 19.73 <.001 .85 Intercept 1.45 .16 74.54 15.54 <.001 .76
t0 – t1 −.25 .15 74.06 −1.72 .09 .04 t2 – t0 .50 .14 73.68 3.48 .001 .14
t0 – t2 −.50 .14 73.68 −3.48 .001 .14 t2 – t1 .25 .15 70.86 1.65 .10 .04
Condition (t0) .30 .21 66.51 1.42 .16 .03 Condition (t2) −.58 .22 73.18 −2.64 .01 .09
t0 – t1 * Condition −.82 .20 72.83 −4.07 <.001 .19 t2 – t0* Condition .88 .20 72.79 4.41 <.001 .21
t0 – t2 * Condition −.88 .20 72.79 −4.41 <.001 .21 t2 – t1* Condition .07 .20 70.84 .32 .75 .001
Sleep Diary: Sleep Efficiency (SE)
Model 1 B SE df T p r p 2 Model 2 B SE df t p r p 2
Intercept 79.81 2.12 56.61 37.62 < .001 .96 Intercept 80.01 2.15 59.06 37.17 < .001 .95
t0 – t1 2.04 1.73 69.01 1.18 .24 .02 t2 – t0 −.20 1.77 69.40 −.11 .91 .0002
t0 – t2 .20 1.77 69.40 .11 .91 .0002 t2 – t1 1.84 1.77 69.40 1.04 .30 .02
Condition (t0) −6.77 2.94 57.64 −2.30 .03 .08 Condition (t2) 6.13 2.96 58.94 2.07 .04 .07
t0 – t1 * Condition 11.67 2.41 69.18 4.85 < .001 .25 t2 – t0* Condition −12.90 2.46 69.57 −5.25 < .001 .28
t0 – t2 * Condition 12.90 2.46 69.57 5.25 < .001 .28 t2 – t1* Condition −1.23 2.44 69.38 −.50 .62 .004
Sleep Diary: Time in Bed (TIB)
Model 1 B SE df t p r p 2 Model 2 B SE df t p r p 2
Intercept 520.97 18.11 49.34 28.76 < .001 .94 Intercept 525.35 18.30 51.08 28.71 < .001 .94
t0 – t1 3.40 12.38 69.04 .28 .78 .001 t2 – t0 −4.39 12.65 69.30 −.35 .73 .002
t0 – t2 4.39 12.65 69.30 .35 .73 .002 t2 – t1 −.98 12.65 69.30 −.08 .94 .0001
Condition (t0) 1.31 25.04 50.07 .05 .96 <.0001 Condition (t2) −67.81 25.18 50.99 −2.69 .01 .12
t0 – t1 * Condition −80.64 17.20 69.15 −4.69 < .001 .24 t2 – t0* Condition 69.11 17.56 69.41 3.94 < .001 .18
t0 – t2 * Condition −69.11 17.56 69.41 −3.94 < .001 .18 t2 – t1* Condition −11.53 17.40 69.29 −.66 .51 .01
Sleep Diary: Total Sleep Time (TST)
Model 1 B SE df t p r p 2 Model 2 B SE df t p r p 2
Intercept 413.49 15.97 46.18 25.89 < .001 .94 Intercept 419.95 16.11 47.56 26.08 < .001 .93
t0 – t1 12.00 9.78 68.90 1.23 .22 .02 t2 – t0 −6.46 10.00 69.11 −.65 .52 .01
t0 – t2 6.46 10.00 69.11 .65 .52 .01 t2 – t1 5.53 10.00 69.11 .55 .58 .004
Condition (t0) −33.05 22.06 46.76 −1.50 .14 .05 Condition (t2) −27.39 22.16 47.49 −1.24 .22 .03
t0 – t1 * Condition −6.08 13.59 68.99 −.45 .66 .003 t2 – t0* Condition −5.66 13.88 69.20 −.41 .69 .002
t0 – t2 * Condition 5.66 13.88 69.20 .41 .69 .002 t2 – t1* Condition −11.74 13.75 69.10 −.85 .40 .01
Sleep Diary: Sleep Onset Latency (SOL)
Model 1 B SE df t p r p 2 Model 2 B SE df t p r p 2
Intercept 24.20 3.51 79.55 6.89 < .001 .37 Intercept 23.92 3.59 82.60 6.66 < .001 .35
t0 – t1 −2.97 3.82 69.35 −.78 .44 .01 t2 – t0 .28 3.89 70.10 .07 .94 .0001
t0 – t2 −.28 3.89 70.10 −.07 .94 .0001 t2 – t1 −2.69 3.89 70.10 −.69 .49 .01
Condition (t0) 8.63 4.88 80.87 1.77 .08 .04 Condition (t2) −9.51 4.94 82.45 −1.92 .06 .04
t0 – t1 * Condition −13.85 5.30 69.67 −2.61 .01 .09 t2 – t0* Condition 18.14 5.40 70.42 3.36 .001 .14
t0 – t2 * Condition −18.14 5.40 70.42 −3.36 .001 .14 t2 – t1* Condition 4.30 5.35 70.06 .80 .43 .01
Sleep Diary: Wake After Sleep Onset (WASO)
Model 1 B SE df t p r p 2 Model 2 B SE df t p r p 2
Intercept 37.90 7.28 53.60 5.21 < .001 .34 Intercept 31.36 7.28 53.60 4.31 < .001 .26
t0 – t1 −9.58 5.51 65.93 −1.74 .09 .04 t2 – t0 6.54 5.63 66.28 1.16 .25 .02
t0 – t2 −6.54 5.63 66.28 −1.16 .25 .02 t2 – t1 −3.04 5.51 65.93 −.55 .58 .005
Condition (t0) 16.24 10.01 53.50 1.62 .11 .05 Condition (t2) −1.23 10.08 54.53 −.12 .90 .0003
t0 – t1 * Condition −15.61 7.66 66.36 −2.04 .05 .06 t2 – t0* Condition 17.48 7.83 66.69 2.23 .03 .07
t0 – t2 * Condition −17.48 7.83 66.69 −2.23 .03 .07 t2 – t1* Condition 1.87 7.68 65.92 .24 .81 .001
Fatigue Symptom Inventory (FSI)
Model 1 B SE df t p r p 2 Model 2 B SE df t p r p 2
Intercept 58.00 5.92 57.81 9.80 <.001 .62 Intercept 44.07 6.19 65.06 7.12 <.001 .44
t0 – t1 −13.19 5.12 72.06 −2.58 .01 .08 t2 – t0 13.93 5.00 71.78 2.78 .007 .10
t0 – t2 −13.93 5.00 71.78 −2.78 .007 .10 t2 – t1 .74 5.17 69.38 .14 .89 .0003
Condition (t0) −2.35 8.37 57.81 −.28 .78 .001 Condition (t2) −14.33 8.67 63.70 −1.65 .10 .04
t0 – t1 * Condition −2.37 6.99 71.05 −.34 .74 .002 t2 – t0* Condition 11.98 6.98 71.02 1.72 .09 .04
t0 – t2 * Condition −11.98 6.98 71.02 −1.72 .09 .04 t2 – t1* Condition 9.61 7.11 69.36 1.35 .18 .03

Note. In Model 1, reference time point is baseline (t0) and reference condition is enhanced usual care (EUC). In Model 2, reference time point is 1-month follow-up (t2) and reference condition is EUC.