Table 2.

Interactions of baseline diastolic blood pressure and mean arterial pressure with BP intervention on outcomes.

Outcome by BP parameter	Intensive versus standard		For each 10 mm Hg increase		Interaction term*
	HR (95% CI)	P value	HR (95% CI)	P value	P value
Diastolic BP
Stroke	0.80 (0.63, 1.02)	0.074	0.93 (0.83, 1.05)	0.24	0.50
CVD composite	0.86 (0.70, 1.06)	0.15	0.99 (0.89, 1.09)	0.76	0.87
Myocardial Infarction	0.93 (0.59, 1.46)	0.75	1.14 (0.93, 1.41)	0.21	0.31
Mean arterial BP
Stroke	0.81 (0.64, 1.03)	0.084	0.98 (0.89, 1.08)	0.68	0.34
CVD composite	0.87 (0.71, 1.07)	0.18	1.04 (0.95, 1.13)	0.39	0.75
Myocardial Infarction	0.93 (0.59, 1.47)	0.76	1.15 (0.96, 1.38)	0.12	0.20

^*p-value for product term of BP intervention and each 10 mm Hg higher baseline DBP or MAP