Figure 2. T cell intrinsic SLAMF1 is required for T cell survival.
Kinetic analysis of co-transferred splenocytes from TCR transgenic 1807 mice into WT BL6 recipients one, two, and four weeks post cell transfer and vaccination. A. Schematic of congenic adoptive transfer model to study the T cell intrinsic role of SLAMF1. B. Flow cytometry analysis of transferred CD4 T cells by CD90 variant phenotype (previous gates: singlets, live, dump-, CD4+CD8-). C. Absolute number of transferred cells and statistical analysis of flow cytometry in B (* = p<0.05). Whisker plots represent mean with standard deviation. Data representative of three independent experiments (n=5 per group).
