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. 2022 Mar 11;12:4289. doi: 10.1038/s41598-022-08212-1

Table 3.

Genes containing the greatest number of SNPs within the top 5% of iHS scores.

Gene Chr. Selected SNPs1 Beringian SNPs2 |iHS|3 Putative function4
TYRP1 9 7 66 3.30 Melanin production
PTPRD 9 5 42 3.37 Regulation of cell growth, differentiation, tumorigenesis
GOLGA6L4 15 3 10 3.52 Associated with BMI-adjusted waist circumference
RIPK4 21 3 3 3.47 Stratified epithelial development and keratinocyte differentiation
UGT2B7 4 3 8 3.40 Elimination of toxic xenobiotics and endogenous compounds

1 Number of selected Beringian GSPs in the listed gene.

2 Total number of Beringian GSPs in the listed gene.

3 Averaged |iHS| scores for selected GSPs.

4 Functional annotations compiled from GeneCards database34.