Table 3.
Genes containing the greatest number of SNPs within the top 5% of iHS scores.
| Gene | Chr. | Selected SNPs | Beringian SNPs | Putative function | |
|---|---|---|---|---|---|
| TYRP1 | 9 | 7 | 66 | 3.30 | Melanin production |
| PTPRD | 9 | 5 | 42 | 3.37 | Regulation of cell growth, differentiation, tumorigenesis |
| GOLGA6L4 | 15 | 3 | 10 | 3.52 | Associated with BMI-adjusted waist circumference |
| RIPK4 | 21 | 3 | 3 | 3.47 | Stratified epithelial development and keratinocyte differentiation |
| UGT2B7 | 4 | 3 | 8 | 3.40 | Elimination of toxic xenobiotics and endogenous compounds |
Number of selected Beringian GSPs in the listed gene.
Total number of Beringian GSPs in the listed gene.
Averaged |iHS| scores for selected GSPs.
Functional annotations compiled from GeneCards database34.