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. 2022 Mar 11;13:1296. doi: 10.1038/s41467-022-28950-0

Fig. 2. SPN spikes induced by cortical stimulation were potentiated by coincident ChI pause, dopamine activation and depolarisation.

Fig. 2

a Cortical stimulation induced spike activity in SPNs. A representative potentiation (left) and depression (right) in SPNs 30 min after match or mismatch pairings, respectively. b Spike activity in SPNs (mean ± S.E.M.) was potentiated when the light-induced dopamine signal was coincident with ChI pauses (red, p = 0.0227), but not when coincident with excitation of ChIs (light blue, p = 0.0349) or when phasic dopamine was absent (dark blue—no light flashes after BIC, p = 0. 2219). N = 6 neurons in each group, *p < 0.05 (two-tailed paired t test; averaged last 10 min compared to baseline).