Table 3.

Additional variants from sequential rounds of conditioning.

Phenotype (primary variant)	Round	Variant	hg19 chr 6 position	Distance (bp) from primary variant^	p	pcorr*
ADA positive (AA_DRB1_120_32657518_N)
	1	rs3093664	31544641	1004898	1.16E−06	< 0.001
	2	rs3130215	31525911	1023628	2.54E−06	< 0.001
	3	rs9268500	32376516	173023	5.46E−06	< 0.001
	4	rs9268543	32384800	164739	1.11E−08	< 0.001
	5	rs9469069	31866417	683122	4.64E−05	< 0.001
	6	rs3763313	32376470	173069	1.49E−04	0.001
	7	rs3130062	31525911	1023628	1.01E−03	0.006
	8	rs29220	29589665	2959874	1.08E−03	0.010
	9	rs2267635	29592430	2957109	5.86E−04	0.013
	10	rs4713420	30993566	1555973	2.40E−03	0.029
ADA max titer (rs7756741)
	1	AA_DRB1_13_32660109_FG	32552130	31067	4.69E−05	0.002
	2	rs2523453	31368124	1215073	1.49E−05	0.002
	3	rs17496549	32409707	173490	4.92E−04	0.007
	4	AA_C_9_31347600_S	31239620	1343577	9.42E−04	0.015
	5	rs2240804	30920889	1662308	1.93E−03	0.041
	6	rs3763355	32786881	− 203684	2.48E−03	0.056
	7	rs2395171	32394536	188661	3.01E−03	0.093

*p value corrected for multiple testing from 1000 iterations of resampling (Methods). ^positive values are 5' direction, negative are 3'.