14. Meier 2010: first fracture and DMPA use.
Prescriptions (N) | Cases (N) | Controls (N) | OR (95% CI)a | Adjusted OR (95% CI)b | |
Nonuse | ‐ | 15,614 | 64,415 | reference | reference |
Current use |
1 to 2 | 93 | 305 | 1.27 (1.01 to 1.61) | 1.18 (0.93 to 1.49) |
3 to 9 | 209 | 573 | 1.52 (1.30 to 1.79) | 1.36 (1.15 to 1.60) | |
> 10 | 280 | 710 | 1.67 (1.45 to 1.92) | 1.54 (1.33 to 1.78) | |
Past use |
1 to 2 | 620 | 1985 | 1.31 (1.19 to 1.44) | 1.17 (1.07 to 1.29) |
3 to 9 | 529 | 1609 | 1.38 (1.25 to 1.53) | 1.23 (1.11 to 1.36) | |
> 10 | 182 | 533 | 1.45 (1.22 to 1.72) | 1.30 (1.09 to 1.55) |
aCases and controls matched on age, general practice, calendar time, and history in database bAdjusted for body mass index, smoking, asthma, epilepsy; use of progestin‐only preparations, MPA low dose, β‐blockers, proton pump inhibitors, systemic corticosteroids, benzodiazepines, serotonin reuptake inhibitors, anticonvulsants, and contraceptive not under investigation.