Comparison 3. DMPA: use versus nonuse.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Fractures (per woman‐years)	1	1.722356E6	Risk Ratio (M‐H, Fixed, 95% CI)	1.41 [1.35, 1.47]
2 Fractures (per woman‐year) by exposure	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 Low: 1 to 7 DMPA injections	1	1.639319E6	Risk Ratio (M‐H, Fixed, 95% CI)	1.47 [1.40, 1.54]
2.2 High: 8 or more DMPA injections	1	1.478078E6	Risk Ratio (M‐H, Fixed, 95% CI)	1.22 [1.13, 1.32]
3 Fractures (per woman‐years) by site	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 Axial	1	1.722356E6	Risk Ratio (M‐H, Fixed, 95% CI)	0.95 [0.74, 1.23]
3.2 Appendicular skeleton	1	1.722356E6	Risk Ratio (M‐H, Fixed, 95% CI)	1.38 [1.31, 1.46]
3.3 All other fractures	1	1.722356E6	Risk Ratio (M‐H, Fixed, 95% CI)	1.49 [1.39, 1.59]