Skip to main content
. 2022 Jan 24;149(8):dev200139. doi: 10.1242/dev.200139

Fig. 5.

Fig. 5.

WT HSCs transplanted into IL7Rα−/− mice are not capable of reconstituting tissue-resident lymphocytes to steady-state numbers. (A-E) Bar graphs comparing circulating B cells and TLCs at steady state (solid bars) to their reconstitution upon transplantation of WT HSCs (pattern bars). Cellularity of peripheral blood B cells (A), B1a cells (B), MZB (C), ILC2 (D) and Tregs (E) in WT or IL7Rα−/− mice are compared with WT and IL7Rα−/− mice reconstituted with WT HSCs. WT steady state n=11; WT recipient total n=7; IL7Rα−/− steady state n=6; IL7Rα−/− recipient total n=12. Differences were analyzed with one-way ANOVA: peripheral blood B cells P<0.0001; B1a cells P<0.0001; MZB P<0.0001; ILC2 P<0.0001; Tregs P=0.0134. Dunnett multi-parameter test: *P<0.05, **P<0.005, ***P<0.0005, ****P<0.00005. In gray are differences analyzed with unpaired two-tailed Student's t-test as reported in Fig. 4: *P<0.05.