Table 2.
Comparison of CMR findings among T2DM patients with/without AR and normal controls
| Controls (n = 83) | T2DM (AR −) (n = 149) | T2DM (AR +) (n = 66) | |
|---|---|---|---|
| LVEDV, mL | 142.6 (115.6, 187.1) | 135.5 (109.2, 161.0) | 191.0 (136.2, 251.0)*† |
| LVESV, mL | 58.7 (42.8, 95.1) | 49.12 (38.0, 69.8) | 102.6 (56.4, 195.6)*† |
| LVSV, mL | 73.7 (59.9, 95.8) | 78.3 (63.5, 96.6) | 66.0 (48.2, 82.0)*† |
| LVEF, % | 62.0 (41.5, 64.1) | 61.4 (54.3, 66.7) | 43.2 ± 2.6*† |
| LV mass index, (g/m2) | 60.7 ± 11.4 | 59.4 ± 12.1 | 71.9 ± 29.3*† |
| PS (%) | |||
| Radial | 36.6 ± 9.5 | 29.9 (23.8, 37.4)* | 15.3 (9.5, 27.6)*† |
| Circumferential | − 20.0 ± 3.0 | − 19.0 ± 4.5 | − 13.0 ± 5.9*† |
| Longitudinal | − 14.0 ± 3.4 | − 12.2 ± 4.0* | − 7.9 ± 4.2*† |
| PSSR (1/s) | |||
| Radial | 1.54 (1.1, 2.0) | 1.8 (1.3, 2.1)* | 1.0 (0.7, 1.5)*† |
| Circumferential | − 0.9 (− 1.1, − 0.7) | − 1.0 ± 0.4 | − 0.7 ± 0.3*† |
| Longitudinal | − 0.7 (− 0.8, − 0.5) | − 0.7 (− 0.9, − 0.5)* | − 0.5 (− 0.7, − 0.3)*† |
| PDSR (1/s) | |||
| Radial | − 2.7 ± 0.9 | − 1.8 (− 2.3, − 1.2)* | − 1.0 (− 1.6, − 0.6)*† |
| Circumferential | 1.2 ± 0.3 | 1.1(0.9, 1.3)* | 0.7 ± 0.3*† |
| Longitudinal | 0.9 ± 0.3 | 0.7(0.5, 0.9)* | 0.5(0.4, 0.6)*† |
*P < 0.05, T2DM vs. Normal; †P < 0.05, T2DM patients with AR vs. T2DM patients without AR. T2DM type 2 diabetes mellitus, AR aortic regurgitation, LV left ventricular, EDV end diastolic volume, ESV end systolic volume, SV stroke volume, EF ejection fraction, PS peak strain, PSSR peak systolic strain rate, PDSR peak diastolic strain rate