Table 4.

Univariable and multivariable analysis between the magnitude of LV peak strain and clinical indices in T2DM with AR patients

	Radial PS				Circumferential PS				Longitudinal PS
	Univariate	Multivariate			Univariate	Multivariate			Univariate	Multivariate
	R	Β (R = 0.338)	P	95%CI	R	Β (R = 0.450)	P	95%CI	R	Β (R = 0.393)	P	95%CI
Regurgitation degree	− 0.579*	− 0.577	< 0.001	− 8.776 to − 5.627	− 0.653*	− 0.662	< 0.001	− 3.160 to − 4.487	− 0.608*	− 0.621	< 0.001	− 2.298 to -3.407
Gender#	− 0.059*	− 0.148	0.014	− 0.85 to − 7.543	− 0.055*	− 0.181	0.002	− 3.364 to − 0.814	− 0.022*	− 0.183	0.009	-2.766 to -0.408
Fasting plasma glucose	0.185*	0.248	0.169	–	0.125	0.1	0.652	–	− 0.183*	− 0.064	0.231	–
HbA1c %	− 0.122*	− 0.046	0.542	–	− 0.130	–	–	–	− 0.226*	− 0.195	0.187	–
Age (years)	− 0.19*	0.105	0.868	–	− 0.179*	0.042	0.811	–	0.178*	0.034	0.38	–
Years with diabetes	− 0.063	–	–	–	− 0.036	–	–	–	0.099	0.05	0.499	–
BMI (kg/m2)	− 0.032	–	–		− 0.016	–	–	–	0.123	0.098	0.142	–
SBP (mmHg)	0.071	–	–		− 0.050	–	–	–	0.061	–	–	–
DBP (mmHg)	− 0.093	–	–		− 0.074	–	–	–	0.141	–	–	–
TG (mmol/l)	− 0.003	–	–		− 0.006	–	–	–	− 0.003	–	–	–
TC (mmol/l)	0.143	–	–		0.192*	0.31	0.774	–	− 0.185*	− 0.105	0.130	–
HDL (mmol/l)	0.070	–	–		0.157*	1.001	0.078	–	− 0.033	–	–	–
LDL (mmol/l)	0.063	–	–		0.100	–	–	–	− 0.082	–	–	–

*P < 0.1 were included in the stepwise multiple linear regression model. ^#For gender, we used 0 to represent for female and 1 to represent for male

PS peak strain, HbA1c glycated haemoglobin, TC total cholesterol, TG triglycerides, HDL high-density lipoprotein, LDL low-density lipoprotein, CI confidence intervals