Table 1.

Demographic and preoperative data

	Duloxetine (50)	Placebo (50)	P
Age	67.8 ± 10.12	66.2 ± 9.83	0.430
Female	30 (60%)	27 (54%)	0.622
Height	1.58 ± 0.08	1.60 ± 0.09	0.243
Weight	62.97 ± 10.21	63.13 ± 9.92	0.937
BMI	24.67 ± 4.35	24.83 ± 3.87	0.846
rVAS	3.47 ± 1.77	3.62 ± 2.02	0.694
aVAS	6.31 ± 2.35	6.52 ± 2.60	0.673
aROM	100.37 ± 14.21	102.72 ± 13.52	0.399
pROM	104.12 ± 14.69	107.29 ± 14.37	0.278
ASA ІІ/ІІІ	43/7	47/3	0.182
HAMD	3.2 ± 1.1	3.1 ± 1.1	0.650
HAMA	3.1 ± 1.3	3.3 ± 1.2	0.426
Kellgren-Lawrence (K-L) grade III/IV	37/13	36/14	0.822
Preoperative medications
NSAIDs	12 (24)	15 (30)	0.499
Acetaminophen	2 (4)	2 (4)	1.000
Opioids	0	0	1.000
Antidepressant	0	0	1.000