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. 2022 Mar 12;22:116. doi: 10.1186/s12935-022-02536-8

Fig. 7.

Fig. 7

LRP11-AS1 promoted the growth and metastasis of TNBC cells by targeting the miR-149-3p/NRP2 axis. A graphic description of the mechanisms underlying the oncogenic role of LRP11-AS1 in TNBC cells. The overexpression of LRP11-AS1 in TNBC suppressed the expression of miR-149-3p and therefore, enhanced the expression of NRP2, which resulted in the promotion of the growth and metastasis of TNBC cells. LRP11-AS1 exhibited the malignant behavior in TNBC by sponging miR-149-3p and regulating the miR-149-3p/NRP2 axis