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. 2022 Mar 12;17:159. doi: 10.1186/s13018-022-03059-8

Fig. 6.

Fig. 6

Circ_0001174 serves as a sponge for miR-186-5p. A Bioinformatics analysis showed that miR-186-5p is a potential target of circ_0001174. B, C Expression of miR-186-5p was significantly downregulated in OS tissues and cell lines. D Circ_0001174 expression was negatively correlated with miR-186-5p expression in OS tissues. E After MG63 cells were transfected with si-circ_0001174, miR-186-5p expression was significantly upregulated, which was reversed by miR-186-5p inhibitor