Table 1.
Literature review of Adie’s pupil cases from 2010 to 2020.
| Literature review | Sex/age | Clinical manifestations | Unilateral/bilateral | Response to dilute pilocarpine | Accompanied disease | Treatment |
|---|---|---|---|---|---|---|
| Takata [7] | Male/30 | Blurred vision | Left | Left pupil constriction (0.125%) | Neurosyphilis | Penicillin G |
| Camoriano [8] | Male/39 | Blurred vision | Right | Right pupil constriction (0.125%) | Neurosyphilis | Penicillin G |
| Jivraj [9] | Female/38 | Blurred vision | Bilateral | Bilateral pupil constriction (0.1%) | Neurosyphilis | Penicillin G |
| Rissardo [10] | Male/23 | Blurred vision | Left | NA | Neurosyphilis | Penicillin G |
| Gu [11] | Male/41 | Blurred vision | Left | Left pupil constriction (0.5%) | Neurosyphilis | Ceftriaxone |
| Pecero-Hormigo [12] | Male/33 | Blurred vision | Right | NA | Neurosyphilis | Penicillin G |
| Reyes [13] | Male/30 | No | Bilateral | Bilateral pupil constriction (0.125%) | Neurosyphilis AIDS |
Penicillin G |
| Cerny [14] | Female/38 | Blurred vision, pain behind the eyeball, photophobia | Bilateral | Bilateral pupil constriction (0.1%) | AIDS | Tenofovir |
| Ortiz-Seller [15] | Female/51 | Blurred vision, pain behind the eyeball | Bilateral | Bilateral pupil constriction (0.1%) | COVID-19 | Oral prednisone |
| Ordás [16] | Male/62 | Blurred vision, diplopia | Left | Left pupil constriction (0.125%) | COVID-19 | Oral prednisone |
| Karadžić [17] | Female/59 | Blurred vision | Left | Left pupil constriction (0.125%) | Viral hepatitis | NA |
| Karadžić [17] | Female/55 | No | Left | Left pupil constriction (0.125%) | Viral hepatitis | NA |
| Lana-Peixoto [18] | Female/33 | No | Left | Left pupil constriction (0.1%) | Leprosy | NA |
| Lana-Peixoto [18] | Female/42 | No | Bilateral | Bilateral pupil constriction (0.1%) | Leprosy | Steroid, anti-leprosy drugs |
| Bhagwan [19] | Female/35 | Blurred vision, redness of both eyes | Bilateral | Bilateral pupil constriction (0.1%) | Sjogren syndrome | NA |
| Bhagwan [19] | Female/45 | Blurred vision | Bilateral | Bilateral pupil constriction (0.1%) | Sjogren syndrome | IVIg |
| Miranda [20] | Female/51 | No | Right | Right pupil constriction (0.125%) | Sjogren syndrome | NA |
| Robles-Cedeño [21] | Female/23 | Blurred vision, diplopia, photophobia | Bilateral | Bilateral pupil constriction (0.125%) | VKH syndrome | Steroid |
| Narang [22] | Male/28 | Blurred vision | Bilateral | Bilateral pupil constriction (0.16%) | VKH syndrome | IVMP |
| Garza [23] | Female/37 | Blurred vision, redness of both eyes | Bilateral | Bilateral pupil constriction (0.16%) | VKH syndrome | Prednisolone, tropicamide-phenylephrine, betamethasone |
| Sevketoglu [24] | Male/5 | No | Left | Left pupil constriction (0.125%) | GBS | Plasmapheresis, IVIg |
| Escorcio-Bezerra [25] | Female/23 | Blurred vision, diplopia | Bilateral | Bilateral pupil constriction (0.125%) | CIDP | Plasmapheresis, corticoids |
| Matalia [26] | Female/16 | Blurred vision | Right | Right pupil constriction (0.125%) | Takayasu arteritis | NA |
| Kaymakamzade [27] | Male/17 | Diplopia | NA | NA | MFS | IVIg |
| Kaymakamzade [27] | Male/66 | Diplopia | Bilateral | Bilateral pupil constriction (0.125%) | MFS | IVIg |
| Morimoto [28] | Female/42 | Photophobia | Left | Left pupil constriction (0.125%) | AAG | IVIg, IVMP |
| Peyman [29] | Female/45 | Blurred vision photophobia | Left | Left pupil constriction (0.1%) | Breast cancer | NA |
| Srinivasan [30] | Male/7 | No | Bilateral | Bilateral pupil constriction (0.125%) | Hodgkin lymphoma | Chemotherapy |
| Horta [31] | Male/48 | No | Left | NA | Hodgkin lymphoma | Chemotherapy |
| Zhang [32] | Female/50 | No | Right | Right pupil constriction (0.0625%) | Mediastinal small cell carcinoma | Chemotherapy |
| Yamane [33] | Female/50 | Blurred vision | Left | Left pupil constriction (0.125%) | Adenoid cystic carcinoma | NA |
| Han [34] | Female/36 | Blurred vision | Bilateral | Bilateral pupil constriction (0.125%) | Dorsal midbrain syndrome | Surgery |
| Kim [35] | Female/2 | No | Left | Left pupil constriction (0.1%) | Inferior oblique myectomy | NA |
| Babiano [36] | Male/NA | No | Right | Right pupil constriction (0.125%) | Traumatic brain injury | NA |
| Tafakhori [37] | Female/27 | Blurred vision | Left | Left pupil constriction (0.125%) | Migraine | Pilocarpine (0.125%) |
| Garrick [38] | Female/22 | No | NA | Pupil constriction | Dysautonomia | IVIg |
| Colak [39] | Female/31 | Blurred vision | Left | Left pupil constriction (0.5%) | No | NA |
| Batawi [40] | Male/40 | Blurred vision, photophobia | Right | Right pupil constriction (0.1%) | No | Pilocarpine (1%) |
| Durán-Ferreras [41] | Female/16 | Blurred vision | Right | Right pupil constriction (0.125%) | No | NA |
| Rivero Rodríguez [42] | Female/21 | Blurred vision, photophobia | Left | Left pupil constriction (0.125%) | No | NA |
NA – not available; AAG – autoimmune autonomic ganglionopathy; AIDS – acquired immunodeficiency syndrome; CIDP – chronic inflammatory demyelinating polyneuropathy; COVID-19 – coronavirus disease 2019; GBS – Guillain-Barre syndrome; IVIg – intravenous immunoglobulin; IVMP – intravenous methylprednisolone; MFS – Miller Fisher syndrome; VKH syndrome – Vogt-Koyanagi-Harada syndrome.