Table 2.
Model | ||||
---|---|---|---|---|
Crude | Adjusted 1 | Adjusted 2 | Adjusted 3 | |
Predictor | AIC = 33 657.40 | AIC = 33 654.66 | AIC = 33 550.92 | AIC = 31 042.23 |
Combination pills v. no contraception (time 1 month) | 1.73 (1.44–2.08) | 1.73 (1.44–2.08) | 1.71 (1.42–2.06) | 1.56 (1.30–1.88) |
Combination pills v. no contraception (time 3 months) | 1.61 (1.38–1.88) | 1.61 (1.38–1.89) | 1.60 (1.37–1.87) | 1.47 (1.26–1.72) |
Combination pills v. no contraception (time 6 months) | 1.47 (1.28–1.68) | 1.47 (1.28–1.68) | 1.45 (1.26–1.67) | 1.36 (1.18–1.56) |
Combination pills v. no contraception (time 12 months) | 1.25 (1.06–1.47) | 1.25 (1.06–1.47) | 1.24 (1.05–1.46) | 1.19 (1.01–1.40) |
Progestin-only pills v. no contraception (time 1 month) | 2.78 (2.14–3.62) | 2.77 (2.13–3.61) | 2.70 (2.08–3.51) | 2.13 (1.64–2.77) |
Progestin-only pills v. no contraception (time 3 months) | 2.53 (2.03–3.15) | 2.52 (2.02–3.14) | 2.46 (1.97–3.07) | 1.96 (1.57–2.44) |
Progestin-only pills v. no contraception (time 6 months) | 2.23 (1.84–1.70) | 2.22 (1.83–1.70) | 2.17 (1.79–2.63) | 1.75 (1.44–2.12) |
Progestin-only pills v. no contraception (time 12 months) | 1.82 (1.44–2.31) | 1.82 (1.44–2.30) | 1.78 (1.41–2.25) | 1.48 (1.17–1.87) |
Parental education, mid v. low | 0.74 (0.56–0.97) | 0.76 (0.58–1.00) | 0.79 (0.60–1.04) | |
Parental education, high v. low | 0.69 (0.53–0.91) | 0.73 (0.56–0.96) | 0.75 (0.57–0.98) | |
Parental suicidal attempt | 3.51 (2.87–4.29) | 2.21 (1.80–2.71) | ||
DAD | 20.10 (17.73–22.79) | |||
BPN (lifetime) | 31.27 (27.14–36.04) |
DAD, depressive and anxiety disorders; BPN, bipolar disorder and non-affective psychosis.
HRs for suicidal behavior at specific time points after the onset of oral contraceptive use are presented. See Fig. 1 for the overall trajectory of risk