Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 12;211:113047. doi: 10.1016/j.envres.2022.113047

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 Elsevier Inc. All rights reserved.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Fig. 5 — Recombination in the spike gene of SARS-CoV-2. (A) Compared the phylogenetic tree using the spike gene without S1-NTD of SARS-CoV-2 related bat/Pangolin viruses with the S1-NTD-based phylogenetic group. The first tree was constructed using SARS-CoV-2 related bat/pangolin viruses spike gene without S1-NTD. The second tree utilized only S1-NTD nucleotide sequences of SARS-CoV-2 related bat/pangolin viruses. (B to E) Phylogenetic tree generated from the RDP using the complete spike sequences of the SARS-CoV-2 related bat/pangolin viruses. The recombination events in the spike gene S1-NTD of SARS-CoV-2 and its related bat/pangolin viruses are supported by RDP, GENECONV, MaxChi, Chimaera, SiScan, and 3Seq. The RDP-based phylogenetic tree using (B) complete spike gene with UPGMA phylogenetic analysis; (C) non-recombinant regions of the entire spike gene with FastNJ phylogenetic analysis; (D) recombinant region of spike gene 1–867 nts (S1-NTD) with UPGMA phylogenetic analysis and 3694–3864 nts; and (E) recombinant region of the spike gene 868–3693 nts with UPGMA phylogenetic analysis.