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. Author manuscript; available in PMC: 2022 Mar 12.
Published in final edited form as: Clin Chem. 2011 Aug 22;57(10):1444–1451. doi: 10.1373/clinchem.2011.163139

Table 2.

Activity values (μmol/L/h) between microplate and microfluidics methods.a

Pompe (GAA) Fabry (GLA)
Enzyme activity Microplate (Duke) Microfluidics (ALL) Microplate (Duke) Microfluidics (ALL)
Normal Affected Normal Affected Normal Affected Normal Affected
Mean 7.9 0.4 21.9 2.3 12.9 2.1 16.9 1.8
Maximum 14.6 0.9 43.5 4.7 28.3 3.2 33.2 3.4
Minimum 3.2 0 10.9 1.1 4.5 0.9 5.9 0.5
a

Normal sample size is 60 DBSs. Affected sample size is 11 DBSs for Fabry and 10 DBSs for Pompe.